Decoding the biosynthetic pathway of the anticancer alkaloid piperlongumine in Piperaceae plants

Milana Perković*, Tito Damiani, Tereza Čalounová, Tomáš Pluskal

Piperaceae plants have been traditionally used to alleviate cancer-like symptoms.1 Piperlongumine is a major bioactive alkaloid produced by Piper species, which demonstrated selective in vitro and in vivo cytotoxicity against various human cancer cell lines by triggering apoptotic and autophagic cell death

Presenting author
Milana Perkovic

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