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  • It was discovered that naltrexone and bupropion combined, which can be marketed in the future as Contrave, have better weight loss results than eating and working out alone. Using two separate drugs to lose weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err on the side of caution and allow the FDA do its job and demand some research be done in order that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on the medications. Researchers found that participants taking this drug to get a year, dropped excess weight within 4 weeks and have kept the load off during the entire 56 weeks with the study. Contrave is a combination from the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, which may make them far better and safer. Combo-pilling is the newest fad or in addition to this the newest to come under scrutiny and thus it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that as of right now there are not any long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug also can raise blood pressure and heart rate, and really should not be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure level, in addition to by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients which has a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation. Follow Crash Test Addict on: Twitter Facebook Linkedin Wordpress

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