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  • Contrave is looking very promising for those seeking a diet plan pill that works well. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs the risk of a possible surge in blood pressure. Using two separate drugs to lose weight can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err on the side of caution and allow the FDA do its job and demand some study be done so your public recognizes the side effects and dangers of the medications before we drive them. Keep in mind that drug companies come in business to generate money and that they would say everything to keep people on their own medications. Researchers found that participants using this drug for any year, dropped excess weight within 4 weeks and have kept the body weight off through the entire 56 weeks with the study. Contrave is a combination in the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs that are made up of many active ingredient, which might make them more efficient and safer. Combo-pilling could be the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that by right now there are no long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure level and heart rate, and mustn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. "This is the first drug I'm alert to that targets both appetite and reward centres in the brain," he said.

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